Receptor, Transforming Growth Factor-beta Type I

**Definition:** A transmembrane serine-threonine kinase that forms a heteromeric complex with TYPE II TGF-BETA RECEPTORS to bind TGF-BETA and regulate a variety of physiological and pathological processes including CELL CYCLE ARREST; CELL PROLIFERATION; CELL DIFFERENTIATION; WOUND HEALING; EXTRACELLULAR MATRIX production, immunosuppression and ONCOGENESIS.

**Tree numbers:** - D08.811.913.696.620.682.700.789 - D12.776.476.563.789 - D12.776.543.750.705.852.720.500 - D12.776.543.750.750.400.820.750

**Synonyms:** - Receptor, TGF-beta Type I - TGF-beta Receptor Protein Kinase - TGF-beta Type I Receptor - TGF-beta Type I Receptors - TbetaR-I Kinase - Activin Receptor-like Kinase 5 - Serine-Threonine-Protein Kinase Receptor R4 - Transforming Growth Factor beta Receptor I - Transforming Growth Factor, beta Receptor 1 - Type I TGF-beta Receptors - Type I TGF-beta Receptor - TGFBR1 - TGF-beta RPK