Receptor, Transforming Growth Factor-beta Type II

**Definition:** A transmembrane serine-threonine kinase that forms a heteromeric complex with TYPE I TGF-BETA RECEPTORS when bound to TGF-BETA. This receptor complex regulates a variety of physiological and pathological processes including CELL CYCLE ARREST; CELL PROLIFERATION; CELL DIFFERENTIATION; WOUND HEALING; EXTRACELLULAR MATRIX production, immunosuppression and ONCOGENESIS.

**Tree numbers:** - D08.811.913.696.620.682.700.795 - D12.776.476.563.795 - D12.776.543.750.705.852.720.750 - D12.776.543.750.750.400.820.875

**Synonyms:** - TGF-beta Type II Receptor - TGF-beta Type II Receptors - TbetaR-II Kinase - Transforming Growth Factor-beta Type II Receptor - Transforming Growth Factor-beta Type II Receptors - Type II TGF-beta Receptor - TGFBR2 - Type II TGF-beta Receptors