Locked-In Syndrome

**Definition:** Acquired neuromuscular disorder characterized by complete paralysis of voluntary muscles and lower CRANIAL NERVES except for limited voluntary eye movements. It is due to various cerebrospinal disconnections at or near the PONS and the POSTERIOR CRANIAL FOSSA, typically secondary to pontine hemorrhage or infarct. Because cognitive function is intact it is sometimes referred to as a pseudocoma state.

**Tree numbers:** - C10.597.622.760.500 - C10.668.416 - C23.888.592.636.786.500

**Synonyms:** - Ventral Pontine Syndrome - Cerebromedullospinal Disconnection