Cytokine Release Syndrome

**Definition:** A severe immune reaction characterized by excessive release of CYTOKINES. Symptoms include DYSPNEA; FEVER; HEADACHE; HYPOTENSION; NAUSEA; RASH; TACHYCARDIA; HYPOXIA; HYPERFERRITINEMIA, and MULTIPLE ORGAN FAILURE. It is associated with viral infections, SEPSIS; AUTOIMMUNE DISEASES and a variety of factors used in IMMUNOTHERAPY.

**Tree numbers:** - C23.550.470.790.250 - C23.550.835.900.356

**Synonyms:** - Hypercytokinemia - Cytokine Storm Syndrome