Duocarmycins

**Definition:** A group of pyrroloindole compounds often with additional spirocyclic unit(s) and their analogs originally isolated from STREPTOMYCES. They bind DNA minor grooves with adenine-N3 alkylation activity.

**Tree numbers:** - D03.383.129.578.275 - D03.633.100.473.278

**Synonyms:** - Duocarmycin