Neurosteroids

**Definition:** Endogenous compounds or drugs that affect neuronal excitability through modulation of specific ionotropic receptors (e.g., GABA-A RECEPTORS). Endogenous neurosteroids are steroid hormones de novo synthesized by neurons and glial cells from steroid metabolite precursors (e.g., PREGNENOLONE).

**Tree numbers:** - D04.210.500.625 - D27.505.519.625.544 - D27.505.696.577.544

**Synonyms:** - Neuro-Steroid - Neuro-Steroids - Neuroactive Steroid - Neuroactive Steroids - Neurosteroid