Pyruvate Dehydrogenase Acetyl-Transferring Kinase

**Definition:** A pyruvate dehydrogenase kinase isozyme located in the mitochondria which converts PYRUVATE to ACETYL CoA in the CITRIC ACID CYCLE, phosphorylates SERINE residues on pyruvate dehydrogenase using ATP, and plays a key role in the regulation of GLUCOSE and fatty acid metabolism.

**Tree numbers:** - D08.811.913.696.620.682.700.783 - D12.776.476.563.783

**Synonyms:** - PDH Kinase - Pyruvate Dehydrogenase (Lipoamide) Kinase - Pyruvate Dehydrogenase Kinase - Pyruvate Dehydrogenase (Acetyl-Transferring) Kinase