Antiviral Restriction Factors

**Definition:** A broad category of endogenous host cellular factors upregulated in response to pathogens (i.e., INTERFERON-stimulated genes) and recruited to interfere with VIRAL REPLICATION and/or trigger host antiviral CELLULAR IMMUNE RESPONSE.

**Tree numbers:** - D12.776.066

**Synonyms:** - Host Cell Restriction Factors - Cellular Restriction Factors - Restriction Factors, Antiviral - Antiviral Effectors