Hippo Signaling Pathway

**Definition:** A signaling pathway that plays a key role in regulating tissue and organ growth. The name derives from the protein kinase Hippo (Hpo) found in DROSOPHILA; where mutations of the Hpo gene result in tissue overgrowth and the hippopotamus phenotype.

**Tree numbers:** - G02.111.820.200 - G04.835.300

**Synonyms:** - Hippo Pathway - Hippo Signaling