Cytochrome P-450 CYP2J2

**Definition:** A cytochrome P450 enzyme involved in oxidizing POLYUNSATURATED FATTY ACIDS (PUFA) to PUFA epoxides which function as potent lipid mediators. This enzyme, encoded by CYP2J2 gene, metabolizes ARACHIDONIC ACID to epoxyeicosatrienoic acids (EETs) which produce biological effects including VASODILATION.

**Tree numbers:** - D08.244.453.003 - D08.811.682.690.708.170.005 - D10.251.355.128 - D12.776.422.220.453.005

**Synonyms:** - CYP2J2