Protein Glutamine gamma Glutamyltransferase 2

**Definition:** Calcium-dependent acyltransferase that catalyzes cross-linking of proteins at a GLUTAMINE in one chain with primary amine such as in LYSINE in another chain. In addition it can also accept monoamine substrates to catalyze post-translational modifications (e.g., protein serotonylation).

**Tree numbers:** - D08.811.913.050.200.800.650

**Synonyms:** - Tissue Transglutaminase - Tissue-Type Transglutaminase - Transglutaminase 2 - Transglutaminase C - Transglutaminase II - TGM2 Proteins - TGase II