Hippocampal Sclerosis

**Definition:** Neuronal loss in the hippocampal regions of CA1 and CA4 and less severely CA2 and CA3. Additional loss of hippocampal stratum radiatum, hippocampal atrophy and ASTROGLIOSIS are common. Hippocampal sclerosis is associated with intractable TEMPORAL LOBE EPILEPSY.

**Tree numbers:** - C10.500.507.400.187 - C16.131.666.507.400.187

**Synonyms:** - Ammon Horn Sclerosis