Congenital Cranial Dysinnervation Disorders

**Definition:** Congenital neurodevelopmental diseases characterized by abnormal eye, eyelid, and facial movements. Congenital cranial dysinnervation disorders (CCDDs) are caused by abnormal innervation of CRANIAL NERVES (e.g., CNs III, IV and VI) resulting in aplasia or hypoplasia of the ocular and facial musculature involved in EYE MOVEMENTS.

**Tree numbers:** - C10.292.562.700.375 - C10.500.198 - C11.590.436.400 - C16.131.666.198

**Synonyms:** - Congenital Fibrosis Syndromes - Congenital Cranial Dysinnervation Syndromes - Congenital Innervation Dysgenesis Syndrome