Symptom Burden

**Definition:** The subjective, quantifiable prevalence, frequency, and severity of symptoms placing a physiologic burden on patients and producing multiple negative, physical, and emotional patient responses.

**Tree numbers:** - E05.318.308.980.438.475.456.750 - N05.715.360.300.800.438.375.364.750 - N06.850.520.308.980.438.475.364.750