Solute Carrier Family 12

**Definition:** Inorganic cation-chloride cotransporters mediating the movement of inorganic SODIUM and/or POTASSIUM cations, coupled to the movement of CHLORIDE anions. The solute carrier 12 (SLC12) family can be divided into Na+-dependent SLC12A1-A3 (NKCC1, NKCC2, and NCC) and Na+-independent SLC12A4-A7 (KCC1-KCC4).

**Tree numbers:** - D12.776.157.530.450.250.910 - D12.776.157.530.450.625.875 - D12.776.543.585.450.250.918 - D12.776.543.585.450.625.875

**Synonyms:** - SLC12A Transporters