Calponins

**Definition:** A family of actin binding proteins mostly in smooth muscle. Calponins include most abundant alpha-calponin (h1 or basic); beta-calponin; neutral calponin (h2 calponin); acidic calponin, SM22, and transgelin. Calponin family members have N-terminal single Calponin Homology (CH) domain and multiple C-terminus 23-amino acids long calponin-like repeats called CLICK-23. Calponins participate in modulation of smooth muscle contraction by binding to ACTINS (F- and G-Actins), CALMODULIN and TROPOMYSIN.

**Tree numbers:** - D05.750.078.730.266 - D12.776.157.125.123 - D12.776.210.500.187 - D12.776.220.525.268

**Synonyms:** - Calponin - Calponin Family Proteins