Iodothyronine Deiodinase Type II

**Definition:** An enzyme responsible for T4 (3,5,3',5'-tetraiodothyronine) to T3 (3,5,3'-TRIIODOTHYRONINE) conversion. May contribute to increasing T3 THYROID HORMONE production in patients with GRAVES DISEASE.

**Tree numbers:** - D08.811.682.732.525.500

**Synonyms:** - TXDI2 Enzyme - Selenodeiodinase Type 2 - Type 2 Deiodinase (D2) - Type 2 Selenodeiodinase - Type II 5'-Deiodinase - DIO2 Enzyme - Type II Iodothyronine Deiodinase