First Generation Cephalosporins

**Definition:** CEPHALOSPORIN agents with excellent coverage against gram-positive cocci, such as STAPHYLOCOCCUS and STREPTOCOCCUS. They have some activity against the gram-negative bacteria, but in general, gram-negative activity is decreased compared to 2nd, 3rd, and 4th generation cephalosporins.

**Tree numbers:** - D27.505.954.122.085.386.500

**Synonyms:** - First Generation Cephalosporin