Endothelial PAS Domain-Containing Protein 1

**Definition:** A basic helix-loop-helix transcription factor that regulates expression of genes in response to oxygen, including VASCULAR ENDOTHELIAL GROWTH FACTOR. It plays a role in the development of blood vessels (NEOVASCULARIZATION, PHYSIOLOGIC) and lung tissue.

**Tree numbers:** - D12.776.260.103.594 - D12.776.930.125.594

**Synonyms:** - bHLH-PAS Factor HLF - Endothelial PAS Protein-1 - EPAS1 Protein - HIF-2 alpha - HIF-Related Factor - HIF2alpha Protein - HLF Protein (bHLH-PAS) - HRF Transcription Factor - Hypoxia-Inducible Factor 2, alpha Subunit - Hypoxia-Inducible Factor 2a