Natural Resistance-associated Macrophage Protein 1

**Definition:** A cation transport protein that shares structural homology with prokaryotic and eukaryotic transport proteins. In mammals, it is a MACROPHAGE-specific antiporter, transporting metal ions in either direction against a proton gradient, and localizes to membranes of late ENDOSOMES and LYSOSOMES, where it may contribute to antimicrobial activity.

**Tree numbers:** - D12.776.157.530.450.162.236 - D12.776.157.530.450.250.754 - D12.776.543.550.190.359 - D12.776.543.585.450.162.230 - D12.776.543.585.450.250.695

**Synonyms:** - Natural Resistance-associated Macrophage Protein - Nramp Protein - Nramp1 Protein - SLC11A1 Protein - Solute Carrier 11a1 - Solute Carrier Family 11-(proton-coupled divalent metal ion transporters), Member 1