Dectin-1

**Definition:** A C-type lectin that functions as a pattern recognition receptor on DENDRITIC CELLS and other immune cells. It is specific for beta-1,-linked and beta 1,6-linked GLUCANS that constitute the CELL WALL of pathogenic bacteria and fungi, and is essential for the TOLL-LIKE RECEPTOR 2 INNATE INFLAMMATORY RESPONSE and activation of NF-KAPPA-B.

**Tree numbers:** - D12.776.503.280.343 - D12.776.543.750.705.910.111

**Synonyms:** - CD369 Antigen - Dectin 1 - Dectin1