cGAS-STING Signaling Pathway

**Definition:** A signal transduction pathway that involves cGMP-AMP synthase (cGAS), stimulator of interferon genes (STING), and downstream signaling adaptors. This pathway plays an essential role in the innate immune system by activating immune defenses, particularly against invading pathogens or harmful damage.

**Tree numbers:** - G02.111.820.926 - G04.835.926

**Synonyms:** - (cGAS-STING) Pathway - cGAS-STING cascade - cGAS-STING Signaling - cGAS–STING Cytosolic DNA Sensing Pathway