Proto-Oncogene Protein Spi-1

**Definition:** An ETS MOTIF - containing trans-activator that functions in HEMATOPOIESIS. It activates transcription of critical genes by making genomic regions within HETEROCHROMATIN accessible to other key transcription factors.

**Tree numbers:** - D12.776.260.755.375 - D12.776.624.664.700.203 - D12.776.930.900.475 - D12.776.964.925.984.435

**Synonyms:** - NF-JB Protein - NFbetaA Protein - NFIL-1betaA Protein - c-Spi-1 Protein - PU.1 Protein - Transcription Factor PU.1 - Pu-1 Protein