Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase

**Definition:** A nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP in mammals. This activates the STING1 PROTEIN through the CGAS-STING SIGNALING PATHWAY, which triggers the production of INTERFERON TYPE I and other CYTOKINES.

**Tree numbers:** - D08.811.913.696.445.246

**Synonyms:** - cGAS Protein - Cyclic GMP-AMP Synthase