D000099271Level 8
Prostasin
**Definition:** A serine endopeptidase that has a similar cleavage specificity to TRYPSIN, favoring substrates with poly-basic amino acid sequences. Prostasin plays a critical role in activating EPITHELIAL SODIUM CHANNELS through cleavage of the ENAC gamma subunit.
**Tree numbers:** - D08.811.277.656.300.760.736 - D08.811.277.656.959.350.736
**Synonyms:** - Serine Protease 8
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