Hydroxyacylglutathione Hydrolase

**Definition:** A thiolesterase that catalyzes the production of GLUTATHIONE and D-LACTIC ACID from the hydrolysis of S-D-lactoyl-glutathione. In vertebrates, only one gene that encodes hydroxyacylglutathione hydrolase is known to occur. In yeast and higher plants, separate genes encode the cytosolic and mitochondrial forms of this enzyme.

**Tree numbers:** - D08.811.277.352.897.544

**Synonyms:** - Acetoacetylglutathione Hydrolase - Glo2 Hydrolase Enzyme - Glyoxalase II - HAGH Protein - Hydroxyacyl Glutathione Hydrolase