Dentin Sialophosphoprotein

**Definition:** An extracellular matrix protein that is highly expressed in ODONTOBLASTS. It is cleaved into 2 chains: dentin sialoprotein and dentin phosphoprotein. Mutations in the human DSPP gene, which encodes dentin sialophosphoprotein, can cause DENTINOGENESIS IMPERFECTA.

**Tree numbers:** - D09.400.430.950.001 - D12.644.233.800.001 - D12.776.395.700.001 - D12.776.744.001 - D12.776.860.300.531

**Synonyms:** - Dentin Matrix Protein 3 - Dentin Phosphophoryn - Dentin Phosphoprotein - Dentin Sialoprotein