AIDS-Related Complex

**Definition:** A prodromal phase of infection with the human immunodeficiency virus (HIV). Laboratory criteria separating AIDS-related complex (ARC) from AIDS include elevated or hyperactive B-cell humoral immune responses, compared to depressed or normal antibody reactivity in AIDS; follicular or mixed hyperplasia in ARC lymph nodes, leading to lymphocyte degeneration and depletion more typical of AIDS; evolving succession of histopathological lesions such as localization of Kaposi's sarcoma, signaling the transition to the full-blown AIDS.

**Tree numbers:** - C01.221.250.875.080 - C01.221.812.640.400.080 - C01.778.640.400.080 - C01.925.782.815.616.400.080 - C01.925.813.400.080 - C01.925.839.080 - C12.100.937.640.400.080 - C20.673.480.080

**Synonyms:** - ARC - Lymphadenopathy Syndrome