Alzheimer Disease

**Definition:** A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

**Tree numbers:** - C10.228.140.380.100 - C10.574.945.249 - F03.615.400.100

**Synonyms:** - Alzheimer Syndrome - Alzheimer-Type Dementia (ATD) - Alzheimer's Diseases - Alzheimer Dementia - Alzheimer's Disease - Dementia, Senile - Dementia, Alzheimer Type - Senile Dementia, Alzheimer Type - Alzheimer Type Senile Dementia - Primary Senile Degenerative Dementia - Alzheimer Sclerosis - Dementia, Primary Senile Degenerative