Anti-Inflammatory Agents, Non-Steroidal

**Definition:** Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.

**Tree numbers:** - D27.505.696.663.850.014.040.500 - D27.505.954.158.030 - D27.505.954.329.030

**Synonyms:** - Non-Steroidal Anti-Inflammatory Agent - NSAID - Nonsteroidal Anti-Inflammatory Agent - Anti Inflammatory Agents, Nonsteroidal - Antiinflammatory Agents, Non Steroidal - Antiinflammatory Agents, Nonsteroidal - Non-Steroidal Anti-Inflammatory Agents - Nonsteroidal Anti-Inflammatory Agents - NSAIDs