Antigens, Polyomavirus Transforming

**Definition:** Polyomavirus antigens which cause infection and cellular transformation. The large T antigen is necessary for the initiation of viral DNA synthesis, repression of transcription of the early region and is responsible in conjunction with the middle T antigen for the transformation of primary cells. Small T antigen is necessary for the completion of the productive infection cycle.

**Tree numbers:** - D12.776.624.664.520.090 - D12.776.964.350.062.090 - D12.776.964.700.090 - D23.050.285.062.090 - D23.050.327.062.090

**Synonyms:** - Polyomavirus Transforming Antigens - Polyomavirus Tumor Antigens