Arachidonate 12-Lipoxygenase

**Definition:** An enzyme that catalyzes the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-HPETE) which is itself rapidly converted by a peroxidase to 12-hydroxy-5,8,10,14-eicosatetraenoate (12-HETE). The 12-hydroperoxides are preferentially formed in PLATELETS.

**Tree numbers:** - D08.811.682.690.416.583.500.060 - D12.776.556.579.374.568.500.025

**Synonyms:** - 12-Lipoxygenase - Arachidonic Acid 12-Lipoxygenase