Arachidonate 5-Lipoxygenase

**Definition:** An enzyme that catalyzes the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-HPETE) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-HETE). The 5-hydroperoxides are preferentially formed in leukocytes.

**Tree numbers:** - D08.811.682.690.416.583.500.055 - D12.776.556.579.374.568.500.020

**Synonyms:** - 5-Lipoxygenase - Arachidonic Acid 5-Lipoxygenase - Leukotriene A Synthase - Leukotriene A4 Synthase - Leukotriene A4 Synthetase - LTA4 Synthase