ATP Citrate (pro-S)-Lyase

**Definition:** An enzyme that, in the presence of ATP and COENZYME A, catalyzes the cleavage of citrate to yield acetyl CoA, oxaloacetate, ADP, and ORTHOPHOSPHATE. This reaction represents an important step in fatty acid biosynthesis. This enzyme was formerly listed as EC 4.1.3.8.

**Tree numbers:** - D08.811.913.050.331

**Synonyms:** - ATP Citrate (pro-3S)-Lyase - ATP Citrate Lyase - ATP Citrate Synthase - ATP-Dependent Citrate Lyase - Citrate Cleavage Enzyme