Bartter Syndrome

**Definition:** A group of disorders caused by defective salt reabsorption in the ascending LOOP OF HENLE. It is characterized by severe salt-wasting, HYPOKALEMIA; HYPERCALCIURIA; metabolic ALKALOSIS, and hyper-reninemic HYPERALDOSTERONISM without HYPERTENSION. There are several subtypes including ones due to mutations in the renal specific SODIUM-POTASSIUM-CHLORIDE SYMPORTERS.

**Tree numbers:** - C12.050.351.968.419.815.279 - C12.200.777.419.815.279 - C12.950.419.815.279 - C19.053.800.604.249

**Synonyms:** - Aldosteronism with Hyperplasia of the Adrenal Cortex - Bartter Disease - Bartter's Disease - Bartter's Syndrome - Juxtaglomerular Hyperplasia with Secondary Aldosteronism