Calcium Channel Agonists

**Definition:** Agents that increase calcium influx into calcium channels of excitable tissues. This causes vasoconstriction in VASCULAR SMOOTH MUSCLE and/or CARDIAC MUSCLE cells as well as stimulation of insulin release from pancreatic islets. Therefore, tissue-selective calcium agonists have the potential to combat cardiac failure and endocrinological disorders. They have been used primarily in experimental studies in cell and tissue culture.

**Tree numbers:** - D27.505.519.562.124 - D27.505.696.260.250 - D27.505.954.411.793.205

**Synonyms:** - Calcium Channel Activators - Calcium Channel Agonist