Chlorambucil

**Definition:** A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)

**Tree numbers:** - D02.455.526.728.650.156

**Synonyms:** - Chloraminophene - Chlorbutin - N,N-Di-(2-chloroethyl)-p-aminophenylbutyric Acid - 4-(Bis(2-chloroethyl)amino)benzenebutanoic Acid