Clotrimazole

**Definition:** An imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, an important component of fungal CELL MEMBRANES. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane.

**Tree numbers:** - D03.383.129.308.175

**Synonyms:** - Klotrimazole