Complement C3b Inactivator Proteins

**Definition:** Endogenous proteins that inhibit or inactivate COMPLEMENT C3B. They include COMPLEMENT FACTOR H and COMPLEMENT FACTOR I (C3b/C4b inactivator). They cleave or promote the cleavage of C3b into inactive fragments, and thus are important in the down-regulation of COMPLEMENT ACTIVATION and its cytolytic sequence.

**Tree numbers:** - D12.776.124.486.274.920.325

**Synonyms:** - C3b Inhibitors - Complement 3b Inactivators - Complement 3b Inhibitors - C3b Inactivators - Complement C3b Inhibitor Proteins - Conglutinogen Activating Factors - Complement C3b Inactivators