Complement C7

**Definition:** A 93-kDa serum glycoprotein encoded by C7 gene. It is a polypeptide chain with 28 disulfide bridges. In the formation of MEMBRANE ATTACK COMPLEX; C7 is the next component to bind the C5b-6 complex forming a trimolecular complex C5b-7 which is lipophilic, resembles an integral membrane protein, and serves as an anchor for the late complement components, C8 and C9.

**Tree numbers:** - D12.776.124.486.274.650

**Synonyms:** - C7 Complement - Complement 7 - Complement Component 7