Dianhydrogalactitol

**Definition:** One of the cytotoxic dihalohexitols that alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in a disruption of DNA function and cell cycle arrest. It has antineoplastic activity and also causes bone marrow toxicity.

**Tree numbers:** - D02.033.800.400.350 - D09.853.400.350

**Synonyms:** - Dianhydrodulcitol - Diepoxydulcitol - Diepoxygalactitol - 1,2,5,6-Dianhydrogalactitol - 1,2-5,6-Dianhydrogalactitol