Dihydropteridine Reductase

**Definition:** An enzyme that catalyzes the reduction of 6,7-dihydropteridine to 5,6,7,8-tetrahydropteridine in the presence of NADP+. Defects in the enzyme are a cause of PHENYLKETONURIA II. Formerly listed as EC 1.6.99.7.

**Tree numbers:** - D08.811.682.662.582.361

**Synonyms:** - 6,7-Dihydropteridine Reductase