DNA, Superhelical

**Definition:** Circular duplex DNA isolated from viruses, bacteria and mitochondria in supercoiled or supertwisted form. This superhelical DNA is endowed with free energy. During transcription, the magnitude of RNA initiation is proportional to the DNA superhelicity.

**Tree numbers:** - D13.444.308.283.250 - G02.111.570.820.486.212.250 - G05.360.580.156.250

**Synonyms:** - DNA, Supercoiled - DNA, Supertwisted