gamma-Glutamylcyclotransferase

**Definition:** An enzyme that catalyzes the synthesis of pyroglutamate from a gamma-glutamyl-amino acid, also releasing the free amino acid. The enzyme acts on derivatives of glutamate, 2-aminobutyrate, alanine and glycine. The enzyme has been proposed to have a role in a gamma-glutamyl cycle for amino acid transport into cells in the intestines. EC 2.3.2.4.

**Tree numbers:** - D08.811.913.050.200.400

**Synonyms:** - gamma-Glutamylamine Cyclotransferase