Globosides

**Definition:** Glycosphingolipids containing N-acetylglucosamine (paragloboside) or N-acetylgalactosamine (globoside). Globoside is the P antigen on erythrocytes and paragloboside is an intermediate in the biosynthesis of erythrocyte blood group ABH and P 1 glycosphingolipid antigens. The accumulation of globoside in tissue, due to a defect in hexosaminidases A and B, is the cause of Sandhoff disease.

**Tree numbers:** - D02.065.313.425 - D09.400.410.420.525.200.425 - D10.390.470.675.200.425 - D10.570.877.360.612.200.425