Glucosylceramidase

**Definition:** A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high concentrations of glucosylceramide in the brain in GAUCHER DISEASE. EC 3.2.1.45.

**Tree numbers:** - D08.811.277.450.420.412

**Synonyms:** - Glucosyl Ceramidase - beta-Glucocerebrosidase - Glucocerebrosidase - Glucocerebroside beta-Glucosidase - Glucosylceramide beta-Glucosidase - Glucosylsphingosine Glucosyl Hydrolase - Acid beta-Glucosidase