Guanethidine

**Definition:** An antihypertensive agent that acts by inhibiting selectively transmission in post-ganglionic adrenergic nerves. It is believed to act mainly by preventing the release of norepinephrine at nerve endings and causes depletion of norepinephrine in peripheral sympathetic nerve terminals as well as in tissues.

**Tree numbers:** - D02.078.370.460

**Synonyms:** - ((2-Hexahydro-1(2H)-azocinyl)ethyl)guanidine - Octadine - Oktadin