Guanylyl Imidodiphosphate

**Definition:** A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly to G-protein in the presence of Mg2+. The nucleotide is a potent stimulator of ADENYLYL CYCLASES.

**Tree numbers:** - D03.633.100.759.646.454.504.400 - D13.695.667.454.504.400 - D13.695.827.426.504.400

**Synonyms:** - Guanosine 5'-(Beta,Gamma-Imido)Triphosphate - Guanyl-5'-Imidodiphosphate - Gpp(NH)p - P(NH)PPG - GMP-P(NH)P - GMP-PNP