Hemolytic Plaque Technique

**Definition:** A method to identify and enumerate cells that are synthesizing ANTIBODIES against ANTIGENS or HAPTENS conjugated to sheep RED BLOOD CELLS. The sheep red blood cells surrounding cells secreting antibody are lysed by added COMPLEMENT producing a clear zone of HEMOLYSIS. (From Illustrated Dictionary of Immunology, 3rd ed)

**Tree numbers:** - E01.370.225.812.375 - E05.200.812.375 - E05.478.594.375

**Synonyms:** - Hemolytic Plaque Technic - Jerne's Plaque Technic - Jerne's Plaque Technique