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D006504Level 4

Hepatic Veno-Occlusive Disease

**Definition:** Liver disease that is caused by injuries to the ENDOTHELIAL CELLS of the vessels and subendothelial EDEMA, but not by THROMBOSIS. Extracellular matrix, rich in FIBRONECTINS, is usually deposited around the HEPATIC VEINS leading to venous outflow occlusion and sinusoidal obstruction.

**Tree numbers:** - C06.552.360 - C14.907.460

**Synonyms:** - Hepatic Veno Occlusive Disease - Veno-Occlusive Disease, Hepatic - Sinusoidal Obstruction Syndrome

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